Study Deep Dive

Our Deep dive, translating peer-reviewed research into clear, clinically grounded insights on polyphenol science.

Dandelion and the Gut Ecosystem

Study: Dandelion (Taraxacum officinale) as a Prebiotic Source: Implications for Gut Microbiota, Metabolic Health, and Functional Food Development

Noni Polyphenols and the Gut Microbiome

Study: Bioactivity and Influence on Colonic Microbiota of Polyphenols from Noni (Morinda citrifolia L.) Fruit Under Simulated Gastrointestinal Digestion

Atractylodes and Gut Barrier Health

Study: Protective Effects of Polysaccharide of Atractylodes macrocephala Koidz and Jiawei Si-jun-zi Decoction on Gut Health and Immune Function in Cyclophosphamide-Treated Chicks

Horse Chestnut and Digestive Function

Study: A Review of the Bioactive Components and Pharmacological Properties of Aesculus hippocastanum L. Seeds

Peppermint and Digestive Comfort

Study: Natural Products for the Treatment of Irritable Bowel Syndrome

Quebracho Tannins and IBS Symptoms

Study: Improving Irritable Bowel Syndrome (IBS) Symptoms and Quality of Life with Quebracho and Chestnut Tannin-Based Supplementation: A Single-Centre, Randomised, Double-Blind, Placebo-Controlled Clinical Trial

Polyphenols, the Gut Microbiome, and Mental Health

Study: Dietary Polyphenols as Modulators of the Microbiota–Gut–Brain Axis in Depression and Anxiety: A Preclinical Perspective

A Polyphenol-Based Approach to Reflux Symptoms

Study: Effects of a Polyphenol Nutraceutical Containing Hesperidin, Noni, Dandelion and Atractylodes macrocephala Extracts on GERD Symptoms: A Retrospective Chart Analysis

Can Real-World Patients Benefit from a Polyphenol-Based Approach to IBS-C?

Study: Response of Irritable Bowel Syndrome with Constipation Patients Administered a Combined Quebracho/Conker Tree/M. balsamea Willd Extract

A Polyphenol-Based Approach to Bloating and Constipation

Study: Efficacy of a Quebracho, Conker Tree, and M. balsamea Willd Blended Extract in a Randomized Study in Patients with Irritable Bowel Syndrome with Constipation

Could Atrantil Help Address Methane Overgrowth?

Study: Open-Label Assessment of the Efficacy of Atrantil in the Treatment of Methane-Predominate Intestinal Bacterial Overgrowth

Hesperidin and the Gut Ecosystem

Study: Hesperidin: A Review on Extraction Methods, Stability and Biological Activities

The Ozempic Side Effect Nobody Warned You About: Your Gut Slows Down

Study: GLP-1 Receptor Agonist Use Is Associated With Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth